Hypothesis is that the striatum (box) serves as part of an adaptive motor control system. Both extrinsic signals from the cerebral hemispheres and brainstem and intrinsic signals generated by interneurons and intrinsic circuits contribute to contingent activation of projection neurons and modifiable reset and latch-on functions promoting adaptive adjustments in striatal activity. Basal ganglia output programs contribute to programming and implementation of actions through projections to thalamocortical and brainstem processing networks.
