Edelman;
Neural Darwinism |
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Topic |
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Edelman; Neural Darwinism |
46 |
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Neuronal group -- a collection of cells of similar or variant types, ranging in number from hundreds to thousands, that are closely connected in their intrinsic circuitry and whose mutual dynamic interaction may be further enhanced by increases in synaptic efficacy. |
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Edelman;
Neural Darwinism |
60 |
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Reentry is
essential because of the nature of the parallel
neural process required for categorization of the physical
world and because of the distributed properties of the neural populations that result in degeneracy. |
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Edelman;
Neural Darwinism |
61 |
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In accord with the associative properties of a distributed degenerate
system, each cycle of reentry between any two levels or maps would call upon
a very large number of associable neuronal groups. |
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Edelman;
Neural Darwinism |
61 |
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If dynamic
categorizations are to be carried out disjunctively in an uninstructed system, then at least two different and independent abstractions must be made of a stimulus object or category. This means that a minimum of two independent abstracting networks
must work simultaneously
(and disjunctively)
in response to a stimulus and then interact via
reentry to provide some abstract
higher-order linkage of their representations. |
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Edelman; Neural Darwinism |
63 |
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Reentry within sensory systems
only is not in itself sufficient for adequate functioning of the group
selective system. |
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Edelman; Neural Darwinism |
63 |
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The brain functions for action, and output to the motor systems is required for two
essential tasks. |
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Edelman;
Neural Darwinism |
63 |
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The first task is to aid in selecting appropriate inputs by
altering the relationship of sensory systems to the surroundings by spontaneous or learned movement. |
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Edelman;
Neural Darwinism |
63 |
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Motor systems
must also verify and
corroborate through
actions the instantaneous
and dynamic responses as
well is the enhanced connectivities that result from the action of
groups. |
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Edelman; Neural Darwinism |
111 |
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Cell proliferation to form populations that constitute maps in the CNS is
independent of the mapped input |
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48 |
Edelman; Neural Darwinism |
112 |
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Cell migration -- all neurons in the CNS are gypsies for some part of their career. |
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Edelman;
Neural Darwinism |
114 |
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Selective cell aggregation -- the evidence is compatible with competitive
epigenetic mechanisms consisting of local signals inducing regulation or CAM modulation at the cell surface. |
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Edelman;
Neural Darwinism |
114 |
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Neuronal cytodifferentiation -- overall neuronal shape appears to be genetically
determined; in contrast, arbor distribution and branching is not genetically determined and depends upon input. |
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Edelman; Neural Darwinism |
115 |
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Cell Death
-- Death occurs during patterning, can be stochastic, can involve large numbers of
cells in a population, and is generally not preprogrammed. |
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1 |
Edelman; Neural Darwinism |
115 |
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Formation of Connections -- the outcome of neural process
outgrowth to form and
stabilize connections depends upon a complex set
of cooperative and competitive mechanisms that are dynamic and also to some extent stochastic in their actions. |
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Edelman; Neural Darwinism |
133 |
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Arborization
and Overlap |
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Edelman; Neural Darwinism |
136 |
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Map Changes Linked to Critical Periods |
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3 |
Edelman; Neural Darwinism |
162 |
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Evolutionary Maintenance of Degeneracy in Distributed Systems |
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26 |
Edelman; Neural Darwinism |
163 |
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Overlapping Arbors and Reentrant
Maps |
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Edelman;
Neural Darwinism |
192 |
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Changes in presynaptic
efficacy, the amount
of neurotransmitter released and response to
depolarization of a presynaptic terminal.
The key feature is a long-term shift in the level
of transmitter release at all presynaptic terminals of a neuron as a result of large
fluctuations in the time
averaged instantaneous value of presynaptic efficacy. |
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29 |
Edelman; Neural Darwinism |
204 |
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Relation of Synaptic
Change to Memory |
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Edelman; Neural Darwinism |
204 |
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One of the outstanding
challenges to any general brain theory is to explain the structural
basis of long- and short-term memory. |
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Edelman; Neural Darwinism |
209 |
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Action and Perception |
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5 |
Edelman; Neural Darwinism |
221 |
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Functional Bases of Gestures |
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12 |
Edelman; Neural Darwinism |
240 |
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Categorization and Memory |
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19 |
Edelman; Neural Darwinism |
244 |
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Categorization |
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4 |
Edelman; Neural Darwinism |
247 |
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Perceptual Categorization |
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3 |
Edelman; Neural Darwinism |
251 |
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Object and Auditory Recognition in Infants |
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4 |
Edelman; Neural Darwinism |
268 |
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Like the hippocampus, the cerebellum is assumed to act as a real-time
rehearsal system to connect various unforeseen
portions of synergies
in a smooth sequence;
however, unlike the hippocampus, it proceeds to coordinate
output for action. |
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17 |
Edelman; Neural Darwinism |
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