Edelman; Neural Darwinism
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Edelman; Neural Darwinism 46 Neuronal group -- a collection of cells of similar or variant types, ranging in number from hundreds to thousands, that are closely connected in their intrinsic circuitry and whose mutual dynamic interaction may be further enhanced by increases in synaptic efficacy.
Edelman; Neural Darwinism 60 Reentry is essential because of the nature of the parallel neural process required for categorization of the physical world and because of the distributed properties of the neural populations that result in degeneracy. 14
Edelman; Neural Darwinism 61 In accord with the associative properties of a distributed degenerate system, each cycle of reentry between any two levels or maps would call upon a very large number of associable neuronal groups. 1
Edelman; Neural Darwinism 61 If dynamic categorizations are to be carried out disjunctively in an uninstructed system, then at least two different and independent abstractions must be made of a stimulus object or category.  This means that a minimum of two independent abstracting networks must work simultaneously (and disjunctively) in response to a stimulus and then interact via reentry to provide some abstract higher-order linkage of their representations. 0
Edelman; Neural Darwinism 63 Reentry within sensory systems only is not in itself sufficient for adequate functioning of the group selective system. 2
Edelman; Neural Darwinism 63 The brain functions for action, and output to the motor systems is required for two essential tasks.   0
Edelman; Neural Darwinism 63 The first task is to aid in selecting appropriate inputs by altering the relationship of sensory systems to the surroundings by spontaneous or learned movement. 0
Edelman; Neural Darwinism 63 Motor systems must also verify and corroborate through actions the instantaneous and dynamic responses as well is the enhanced connectivities that result from the action of groups. 0
Edelman; Neural Darwinism 111 Cell proliferation to form populations that constitute maps in the CNS is independent of the mapped input 48
Edelman; Neural Darwinism 112 Cell migration -- all neurons in the CNS are gypsies for some part of their career. 1
Edelman; Neural Darwinism 114 Selective cell aggregation -- the evidence is compatible with competitive epigenetic mechanisms consisting of local signals inducing regulation or CAM modulation at the cell surface. 2
Edelman; Neural Darwinism 114 Neuronal cytodifferentiation -- overall neuronal shape appears to be genetically determined; in contrast, arbor distribution and branching is not genetically determined and depends upon input. 0
Edelman; Neural Darwinism 115 Cell Death -- Death occurs during patterning, can be stochastic, can involve large numbers of cells in a population, and is generally not preprogrammed. 1
Edelman; Neural Darwinism 115 Formation of Connections -- the outcome of neural process outgrowth to form and stabilize connections depends upon a complex set of cooperative and competitive mechanisms that are dynamic and also to some extent stochastic in their actions. 0
Edelman; Neural Darwinism 133 Arborization and Overlap 18
Edelman; Neural Darwinism 136 Map Changes Linked to Critical Periods 3
Edelman; Neural Darwinism 162 Evolutionary Maintenance of Degeneracy in Distributed Systems 26
Edelman; Neural Darwinism 163 Overlapping Arbors and Reentrant Maps 1
Edelman; Neural Darwinism 192 Changes in presynaptic efficacy, the amount of neurotransmitter released and response to depolarization of a presynaptic terminal.  The key feature is a long-term shift in the level of transmitter release at all presynaptic terminals of a neuron as a result of large fluctuations in the time averaged instantaneous value of presynaptic efficacy. 29
Edelman; Neural Darwinism 204 Relation of Synaptic Change to Memory 12
Edelman; Neural Darwinism 204 One of the outstanding challenges to any general brain theory is to explain the structural basis of long- and short-term memory. 0
Edelman; Neural Darwinism 209 Action and Perception 5
Edelman; Neural Darwinism 221 Functional Bases of Gestures 12
Edelman; Neural Darwinism 240 Categorization and Memory 19
Edelman; Neural Darwinism 244 Categorization 4
Edelman; Neural Darwinism 247 Perceptual Categorization 3
Edelman; Neural Darwinism 251 Object and Auditory Recognition in Infants 4
Edelman; Neural Darwinism 268 Like the hippocampus, the cerebellum is assumed to act as a real-time rehearsal system to connect various unforeseen portions of synergies in a smooth sequence; however, unlike the hippocampus, it proceeds to coordinate output for action. 17
Edelman; Neural Darwinism