Squire; Memory and Brain
Book Page   Topic    
Squire; Memory and Brain 5 Santiago Ramon y Cajal (1852-1934)
Squire; Memory and Brain 5 Ivan P. Pavlov (1849-1936) 0
Squire; Memory and Brain 6 Aplysia californica (diagram) 1
Squire; Memory and Brain 17 Donald O. Hebb (1904-1985) 11
Squire; Memory and Brain 19 Schematic diagram of a synapse onto a dendritic spine.  (Diagram) 2
Squire; Memory and Brain 20 Long-term potentiation  (LTP) 1
Squire; Memory and Brain 23 Developing nervous system. Initial oversupply of cells and axon.  Neuronal death and the elimination of collateral branches of neurons. 3
Squire; Memory and Brain 25 In the projection from the lateral geniculate to visual cortex, synapse elimination is especially important in achieving the adult pattern of connectivity 2
Squire; Memory and Brain 26 Pattern of arborization of a single afferent axon in the visual cortex. (Diagram) 1
Squire; Memory and Brain 27 Changes that result from visual experience are reflected directly in the morphology of the terminal fields of the competing axons. 1
Squire; Memory and Brain 29 Competition is most likely a prominent event in the adult nervous system, long after development is complete. 2
Squire; Memory and Brain 31 Hebb synapse plasticity  -- synaptic efficacy would increase between the input cell and a postsynaptic cell in situations where the input successfully fires the postsynaptic cell. 2
Squire; Memory and Brain 32 Effects of experience on the functional connectivity of neural pathways are reflected in morphological change, which depends upon the degree of activity and synchrony in the inputs converging on common targets. 1
Squire; Memory and Brain 32 Remembering and forgetting. 0
Squire; Memory and Brain 33 Forgetting involves actual loss of some of the neural connections that originally represented acquired information. 1
Squire; Memory and Brain 36 Information in long-term memory eventually becomes resistant to forgetting. 3
Squire; Memory and Brain 38 All forgetting, whether it occurs in a few hours or over a period of years, reflects in part an actual loss of information from storage and a corresponding regression of some of the synaptic changes that originally represented the stored information. 2
Squire; Memory and Brain 40 The forebrain in general and neocortex in particular are innervated extrinsically and by several separate, widely projecting ascending fiber systems, each of them linked to a particular neurotransmitter. 2
Squire; Memory and Brain 40 Cortical norepinephrine (NE) originates in the locus coeruleus, a small nucleus in the brainstem at the level of the pons that contains only an estimated 9000 to 16,000 cells in the adult human. 0
Squire; Memory and Brain 40 Locus coeruleus slow conducting axons connect with a number of regions in the brain, notably amygdala, hippocampus, hypothalamus, and thalamus. 0
Squire; Memory and Brain 41 Locus coeruleus is believed to be the only source of NE fibers for most of the forebrain. 1
Squire; Memory and Brain 43 Widely projecting modulatory systems. 2
Squire; Memory and Brain 44 Locus coeruleus neurons, the source of the forebrain NE system, fire in relation to the animal's level of vigilance. 1
Squire; Memory and Brain 56 Set of changes in the nervous system that represents stored memory is commonly known as the engram. 12
Squire; Memory and Brain 77 Memory for whole events is stored widely, not in a single location. Recollection of past events is a reconstruction from fragments, not a veridical playback of past events. 21
Squire; Memory and Brain 143 Little reason to postulate more than two stages of memory, short-term and long-term. 66
Squire; Memory and Brain 145 Information in long-term memory continues to change for many years. Some or all of it can become independent of the medial temporal region (hippocampus). 2
Squire; Memory and Brain 147 Certain short-term forms of synaptic plasticity do not require protein synthesis. 2
Squire; Memory and Brain 149 Long-term memory requires the participation of the medial temporal region, which operates in conjunction with the assemblies of neurons that represent stored information. 2
Squire; Memory and Brain 149 Synaptic plasticity describes a variety of phenomena with different time courses, such as facilitation, post-tetanic potentiation, and long-term potentiation. 0
Squire; Memory and Brain 152 Declarative memory is memory that is directly accessible to conscious recollection. 3
Squire; Memory and Brain 152 Procedural memory is memory that is contained within learned skills or modifiable cognitive operations.  [Stereotyped motor programs]  [FAPs] 0
Squire; Memory and Brain 153 Priming is the facilitation of performance by prior exposure to words or other material. This facilitation occurs despite impared recall or recognition of the same material. 1
Squire; Memory and Brain 158 Priming effects are spared in amnesia. 5
Squire; Memory and Brain 160 The terms 'declarative' and 'procedural' first appeared in the literature of artificial intelligence (1975) and cognitive psychology (1976). 2
Squire; Memory and Brain 161 Priming is a short-lived phenomenon. 1
Squire; Memory and Brain 162 Declarative memory is fast, adaptive for one-trial learning.  In contrast, procedural memory is slow, more automatic, adaptive for incremental learning. 1
Squire; Memory and Brain 164 Procedural memory is not a single thing.  Procedural memory Includes motor skill learning, cognitive skill learning, perceptual learning, classical conditioning, as well as simpler examples of  behavioral plasticity such as habituation, sensitization, and perceptual after-effects. 2
Squire; Memory and Brain 165 Classical conditioning of skeletal musculature depends at least in part on neural pathways in the cerebellum. 1
Squire; Memory and Brain 167 Declarative memory may prove to be a relatively recent evolutionary innovation. 2
Squire; Memory and Brain 167 The specific tightly wired, limited access machinery in the brain  the cognitive unconscious.  [Stereotyped motor programs]  [FAPs] 0
Squire; Memory and Brain 168 Medial temporal region and associated structures of affording animals the capacity for declarative memory. 1
Squire; Memory and Brain 169 Declarative memory can be further subdivided into 'episodic' and 'semantic' memory. 1
Squire; Memory and Brain 169 Episodic memory a reversion memory for past events and an individual's life. 0
Squire; Memory and Brain 169 Semantic memory refers to knowledge of the world.  This system represents organized information such as facts, concepts, and vocabulary. 0
Squire; Memory and Brain 169 Unlike episodic memory, semantic memory has no necessary temporal landmarks. 0
Squire; Memory and Brain 170 Declarative memory includes what can be declared or brought to mind as a proposition or an image. 1
Squire; Memory and Brain 170 Procedural memory includes motor skills, cognitive skills, simple classical conditioning, habituation, sensitization, and other cognitive operations improved by experience. 0
Squire; Memory and Brain 180 Amnesic patients can normal immediate memory and also normal remote memory. 10
Squire; Memory and Brain 186 Medial temporal amnesia. 6
Squire; Memory and Brain 186 Patient H.M. 0
Squire; Memory and Brain 193 Section through the temporal lobe of a normal human brain, showing subicular cortex, presubiculum, subiculum, CA subfields of the hippocampal formation, dentate gyrus. - (photo) 7
Squire; Memory and Brain 195 Both the hippocampus and the amygdala receive information from sensory-specific cortical areas and from multimodal association areas. 2
Squire; Memory and Brain 196 Fornix is only one of two major efferent pathways from the hippocampus. 1
Squire; Memory and Brain 198 Aging and memory. 2
Squire; Memory and Brain 201 Amnesic patients are normal at object-naming tests. 3
Squire; Memory and Brain 202 Amnesia and the functional organization of memory. 1
Squire; Memory and Brain 202 In amnesia, general intellectual ability is intact; short-term memory is intact. 0
Squire; Memory and Brain 204 Within the domain of declarative memory, medial temporal structures are involved only in the establishment and consolidation of long-term memory, not short-term 2
Squire; Memory and Brain 204 Consolidation refers to the ideas that memory storage does not occur instantaneously but instead develops gradually after Initial learning. 0
Squire; Memory and Brain 205 Neural elements and the synaptic connectivity representing information storage are presumed to change gradually over time. 1
Squire; Memory and Brain 205 Consolidation is a competitive process in which some aspects of memory for the original event are forgotten, while those that remain are strengthened. 0
Squire; Memory and Brain 205 Consolidation is a process that occurs within the collection of distributed sites where synaptic change representing information storage has occurred. 0
Squire; Memory and Brain 206 Electroconvulsive therapy (ECT) for depressive illness. 1
Squire; Memory and Brain 209 Retrograde amnesia following medial terminal lobe damage suggests that at the time of learning, the medial temporal region establishes a functional relationship with memory storage sites, especially in neocortex. 3
Squire; Memory and Brain 209 Hippocampal formation can exhibit to long-lasting synaptic change in response to brief, high-frequency stimulation of its input pathway (long-term potentiation, or LTP).  0
Squire; Memory and Brain 209 LTP could be one index of the relationship between hippocampus and neocortex. 0
Squire; Memory and Brain 209 During the lengthy process of consolidation, the critical neural system within the medial temporal region may maintain the organization of distant memory storage sites, until such time as the coherence of these sites increases and they can be activated as an ensemble without the participation of the medial temporal region.  [Gestalts] 0
Squire; Memory and Brain 210 Memory depends on the interaction between a specialized system within the medial temporal region and memory storage sites in neocortex. 1
Squire; Memory and Brain 219 Patients with alcoholic Korsakoff's syndrome commonly have damage to brain stem, cerebellum, and neocortex in addition to specific diencephalic lesions. 9
Squire; Memory and Brain 219 Patients with Korsakoff's syndrome exhibit a severe deficit in remembering the temporal order of learned items. 0
Squire; Memory and Brain 224 Inferotemporal cortex is presumed to both process and store information about the identity of visual objects. 5