Thagard; Brain and the Meaning of Life
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Thagard; Brain and the Meaning of Life 44 Steven Pinker was asked on a TV show to explain in five words or fewer    how the brain works.    Pinker's brilliantly concise response was "Brain cells fire in patterns."
Thagard; Brain and the Meaning of Life 45 Functional model of two connected neurons.  (Diagram) 1
Thagard; Brain and the Meaning of Life 48 Neurons fire in patterns. 3
Thagard; Brain and the Meaning of Life 49 Retrieval of a memory    works by reactivating a pattern of firing    in a population of neurons. 1
Thagard; Brain and the Meaning of Life 49 When you remember something,    it is because your brain has revived patterns    of neural activation. 0
Thagard; Brain and the Meaning of Life 49 Eric Kandel won a Nobel Prize for his research on how learning works    in the sea slug, Aplysia. 0
Thagard; Brain and the Meaning of Life 50 Donald Hebb hypothesized that two neurons that "fire together wire together." 1
Thagard; Brain and the Meaning of Life 51 Literacy    is a recent development in human history,    going back only about 5000 years to the Samarians. 1
Thagard; Brain and the Meaning of Life 52 Because of increased concentrations of the neurotransmitter dopamine,    there is increased activity in the nucleus accumbens,    a brain area associated with feelings of pleasure. 1
Thagard; Brain and the Meaning of Life 52 In addition to increased activity of dopamine,    alcohol also increases activity of the neurotransmitter GABA,    which enables some neurons to inhibit the firing    of other neurons. 0
Thagard; Brain and the Meaning of Life 52 Alcohol's increased activity of GABA,    can produce relaxation in small doses,    but in larger doses can lead to a lack of coordination,    slurring of words,    and even passing out. 0
Thagard; Brain and the Meaning of Life 53 Stimulants such as cocaine and amphetamines,    including the popular drug Ecstasy,    increase brain concentrations of the pleasure-inducing neurotransmitter dopamine, as well as other energizing neurotransmitters such as norepinephrine. 1
Thagard; Brain and the Meaning of Life 53 Opiates such as heroin    stimulate special receptors in the brain    leading to release of dopamine    and subsequent feelings of pleasure and relaxation,    producing strong inclinations toward addiction. 0
Thagard; Brain and the Meaning of Life 53 For depression,    millions of people take drugs like Prozac    that inhibit the reuptake of the neurotransmitter serotonin. 0
Thagard; Brain and the Meaning of Life 53 Some drugs that alleviate depression    may involve the production of new neurons in the hippocampus    as well as increased availability of serotonin    in the synaptic gaps    between existing neurons. 0
Thagard; Brain and the Meaning of Life 53 Bipolar disorder,    formally known as manic depression,    can be effectively treated with lithium,    which affects various neurotransmitters. 0
Thagard; Brain and the Meaning of Life 53 Schizophrenia    can sometimes be treated with drugs    that inhibit dopamine    and also can affect levels of other neurotransmitters. 0
Thagard; Brain and the Meaning of Life 53 Increasing concentrations of dopamine    can alleviate the symptoms of Parkinson's disease. 0
Thagard; Brain and the Meaning of Life 53 The use of recreational and therapeutic drugs    provides overwhelming evidence    that changing brain processes causes changes in mental processes. 0
Thagard; Brain and the Meaning of Life 54 Neural bases of    perception,    memory,    learning,    emotion,    and other mental processes. 1
Thagard; Brain and the Meaning of Life 54 Transcranial magnetic stimulation    that can cause changes in thinking    by noninvasive alteration    of the electrical activity of neurons. 0
Thagard; Brain and the Meaning of Life 61 Artificial intelligence,    which is the construction of computers capable of reasoning and learning.  This view is called functionalism. 7
Thagard; Brain and the Meaning of Life 62 First few decades    of modern research in cognitive science, from the 1950s to the 1970s. 1
Thagard; Brain and the Meaning of Life 63 Much of the most exciting current progress in cognitive science    combines experimental studies of the brain    with computational models    of how it works. 1
Thagard; Brain and the Meaning of Life 65 Inference    is a neural process    involving parallel interactions     among neural populations,    not just a step-by-step linguistic procedure. 2
Thagard; Brain and the Meaning of Life 70 Gestalt figures    such as the reversing duck / rabbit. 5
Thagard; Brain and the Meaning of Life 70 The duck-rabbit inference    consists of the parallel dynamic interaction    of neurons that encode sensory information    with neurons that encode expectations and knowledge    of what ducks and rabbits look like. 0
Thagard; Brain and the Meaning of Life 71 Duck-rabbit reversing figure.  (Diagram) 1
Thagard; Brain and the Meaning of Life 71 Perception    is a kind of inference. 0
Thagard; Brain and the Meaning of Life 71 When we speak or write,    we encounter one sentence at a time,    and seem to infer the next sentence    from the ones that came before,    just as with a proof in mathematics. 0
Thagard; Brain and the Meaning of Life 71 Inference in the brain    does not operate in a serial, step-by-step way.     Each neuron    is synaptically connected    with thousands of others,    so it's firing pattern    is affected by    all of the neurons    that excite or inhibit it,    and it in turn    affects the firing    of all the neurons    that it excites or inhibits.   0
Thagard; Brain and the Meaning of Life 71 Thus inference in the brain is parallel,    in that many neurons    are firing at around the same time,    and asynchronously,    in that there is no central clock    that coordinates the waves of firing    that spread through the neural populations.    Hence perception    is very different    from the kind of serial steps    of linguistic inference. 0
Thagard; Brain and the Meaning of Life 71 Brains perform inferences    using parallel activity    of millions of neurons --    Perception    can elegantly integrate    both bottom-up and top-down information. 0
Thagard; Brain and the Meaning of Life 71 Emotional feelings    involve a dynamic integration    of multiple kinds of information. 0
Thagard; Brain and the Meaning of Life 72 When you smell something,    the smell is the result of a dynamic interaction of different brain areas involving both sensory inputs    and previous knowledge and expectations. 1
Thagard; Brain and the Meaning of Life 72 Perception    requires brains to be able to relate inputs    from the sensory organs    with information that they have already stored    in the form of synaptic connections between neurons. 0
Thagard; Brain and the Meaning of Life 72 Brain is a parallel processor    capable of assessing many aspects simultaneously. 0
Thagard; Brain and the Meaning of Life 72 A few micrograms of a drug like LSD    can disengage your brain's perceptual apparatus    from the usual sensory inputs    and generate fantastic images    that have no correspondence to anything in the world. 0
Thagard; Brain and the Meaning of Life 72 Every night when you dream    your brain generates complex and often compelling sensory experiences    that are not directly caused by anything in the world. 0
Thagard; Brain and the Meaning of Life 76 Constructive nature of perception    with both top-down and bottom-up processing.  [gestalts] 4
Thagard; Brain and the Meaning of Life 96 Feelings of pleasure    and anticipation of desirable outcomes    are associated with circuits of neurons that employ the neurotransmitter dopamine,    running from the ventral tegmental area through the nucleus accumbens to the prefrontal cortex.    Such brain circuits are reciprocal, with many feedback loops. 20
Thagard; Brain and the Meaning of Life 100 Perception    involves simultaneous parallel processing    that combines top-down knowledge    with bottom-up perceptual input. 4
Thagard; Brain and the Meaning of Life 100 Emotions    can be understood as dynamic interactions    of brain areas    that perform both bodily perception    and cognitive appraisal. 0
Thagard; Brain and the Meaning of Life 101 EMOCON model of how different brain areas interact to produce emotions as a result of both cognitive appraisal and bodily perceptions. (diagram) 1
Thagard; Brain and the Meaning of Life 108 When hearing some good news    makes you happy,    the change is the result of your brain's undergoing neural processes    such as activation of your nucleus accumbens. 7
Thagard; Brain and the Meaning of Life 124 A crucial part of the brain's representation of goals    is their association with rewards and punishments. 16
Thagard; Brain and the Meaning of Life 126 Cognitive revolution of the 1960s. 2
Thagard; Brain and the Meaning of Life 127 Artificial intelligence pioneer Marvin Minsky. 1
Thagard; Brain and the Meaning of Life 127 Children    naturally develop strong emotional attachments    to their caregivers,   usually parents.     Caregivers    transmit to children    not only factual information    but also emotional values. 0
Thagard; Brain and the Meaning of Life 133 Psychology is largely concerned with the descriptive task    of saying how people do make decisions,    whereas philosophy is mostly concerned with the normative task of prescribing how people ought to make decisions. 6
Thagard; Brain and the Meaning of Life 135 The brain assesses the priority of goals    using the combined activity of neural populations    involving multimodal representations of situations,    including populations in areas such as the amygdala    required for emotional interpretations. 2
Thagard; Brain and the Meaning of Life 135 Thinking    is often skewed by stimuli    with powerful emotional influences. 0
Thagard; Brain and the Meaning of Life 135 Natural brain tendency    to place more weight    on short-term goals such as eating    than on long-term goals such as being healthy. 0
Thagard; Brain and the Meaning of Life 135 By focusing short-term rewards,    the brain can primarily employ the midbrain dopamine system    rather than the frontal and parietal regions    needed for assessing long-term implications. 0
Thagard; Brain and the Meaning of Life 144 When the parents of Terri Schiavo resisted her husband's decision    to remove her feeding tube in 2005,    she was still important to them,    despite her extensive brain damage.     Her apparent inability to form any representation of anything    seems to suggest that Terri Schiavo's life    really had become meaningless. 9
Thagard; Brain and the Meaning of Life 147 Widows and widowers    require on average seven years    to regain the level of life satisfaction    they had a year before the death of their spouse. 3
Thagard; Brain and the Meaning of Life 148 Marital satisfaction decreases dramatically    after the birth of the first child    and increases only when the last child leaves home. 1
Thagard; Brain and the Meaning of Life 149 A meaningful life    is one where you still have something to do,    even if doing it may not make you happy    every day, week, or year. 1
Thagard; Brain and the Meaning of Life 149 Slacker serenity,     the happiness that supposedly comes from abandoning challenging goals    and simply accepting what you have. 0
Thagard; Brain and the Meaning of Life 149 A source of temporary happiness    can be drugs such as cocaine and heroin    that manipulate the brain's pleasure machinery. 0
Thagard; Brain and the Meaning of Life 152 Love 3
Thagard; Brain and the Meaning of Life 153 When people looked at pictures of their new romantic partners,    their brain showed increased activity    in regions that mediate reward    via the dopamine system,     particularly the ventral tegmental area    and the nucleus accumbens. 1
Thagard; Brain and the Meaning of Life 153 The brain reward areas    activated by thoughts of new romantic partners    are the same areas    activated by reward-producing drugs such as cocaine    that also lead to exhilaration,    sleeplessness,    and loss of appetite. 0
Thagard; Brain and the Meaning of Life 153 Cortical areas associated with emotion    include the insula,    the anterior cingulate,    and the amygdala. 0
Thagard; Brain and the Meaning of Life 153 The fact that viewing a romantic partner    stimulates brain areas associated with reward and pleasure    explains why it feels so good    to fall in love. 0
Thagard; Brain and the Meaning of Life 153 The caudate nucleus of the basal ganglia    contributes to the representation of goals,    expectation of reward,    and integration of sensory inputs    to prepare for action. 0
Thagard; Brain and the Meaning of Life 153 Romantic love    can be viewed as a goal-oriented state    that leads to a set of specific emotions    such as euphoria and anxiety    rather than as an individual specific emotion. 0
Thagard; Brain and the Meaning of Life 153 The neurophysiology of romantic love    seems to differ from that of mere sexual attraction    and also from that of long-term attachment. 0
Thagard; Brain and the Meaning of Life 154 Oxytocin increases trust between strangers. 1
Thagard; Brain and the Meaning of Life 154 Trust is an important part of friendship,    a less intense relationship than romantic love and marriage,    but also of great importance to people's satisfaction with their lives. 0
Thagard; Brain and the Meaning of Life 154 Brain processes involved in interpersonal bonding    have much overlap with those for romantic and familial attachments. 0
Thagard; Brain and the Meaning of Life 154 Spending time with friends is highly pleasurable, involving dopamine brain circuitry. 0
Thagard; Brain and the Meaning of Life 155 Chemical similarities    between social and physical pain;    both are affected by opioids    such as morphine. 1
Thagard; Brain and the Meaning of Life 155 Social threats in humans can lead to decreases in pain sensitivity, just as injury does. 0
Thagard; Brain and the Meaning of Life 155 Social rejection in humans leads to increase blood pressure and levels of the stress hormone cortisol. 0
Thagard; Brain and the Meaning of Life 155 Social and physical pain    have similar mechanisms    that can be understood in terms of brain regions    such as the anterior cingulate    and chemical processes that occur in them. 0
Thagard; Brain and the Meaning of Life 155 People often respond    to the misfortunes of strangers with compassion,    as we see in many acts of charity. 0
Thagard; Brain and the Meaning of Life 156 A full account of the    brain mechanisms underlying love    should be able to accommodate all of its manifestations,    from romance    to friendship    to compassion. 1
Thagard; Brain and the Meaning of Life 156 Pleasure-related brain areas    such as the nucleus accumbens    and circuitry based on neurochemicals    such as dopamine and oxytocin    are highly relevant in the brain mechanisms underlying love. 0
Thagard; Brain and the Meaning of Life 158 Work 2
Thagard; Brain and the Meaning of Life 158 Many people    obtain satisfaction    from their jobs. 0
Thagard; Brain and the Meaning of Life 159 Happiness    does not depend on the absolute amount of wealth,    but rather on how you are doing    compared to others. 1
Thagard; Brain and the Meaning of Life 161 Play 2
Thagard; Brain and the Meaning of Life 162 Children like to roughhouse with each other in ways that are intimately linked to somatosensory information processing within the midbrain, the thalamus, and the cortex. 1
Thagard; Brain and the Meaning of Life 162 Synaptic chemicals that are effective in arousing play include acetylcholine, glutamate, and opioids. 0
Thagard; Brain and the Meaning of Life 162 Fun    of rough-and-tumble play    can continue into adulthood,    through the pursuit of interactive sports. 0
Thagard; Brain and the Meaning of Life 162 Play    produces widespread release    of opioids. 0
Thagard; Brain and the Meaning of Life 162 Activation    of serotonin and noradrenaline systems    reduces play,    and so does blockade    of dopamine systems. 0
Thagard; Brain and the Meaning of Life 162 The evidence seems to suggest    that play is fun    because of its neurochemical effects. 0
Thagard; Brain and the Meaning of Life 162 People enjoy recreational drugs    such as alcohol    because of their effects on various neurochemical pathways,    including ones involving dopamine and endogenous opioids. 0
Thagard; Brain and the Meaning of Life 162 Exercise    can stimulate the production of endorphins,    natural opioids in the brain    that reduce pain    and produce feelings of well-being. 0
Thagard; Brain and the Meaning of Life 163 One of the main sources of entertainment    is music. 1
Thagard; Brain and the Meaning of Life 163 Musical experiences    arise from neural processes    of perception and emotion. 0
Thagard; Brain and the Meaning of Life 163 The ability of people    to reproduce the tempo of a song accurately    is probably due to activity in the cerebellum. 0
Thagard; Brain and the Meaning of Life 163 Listening to music and attending to it structure activates a region of the left frontal cortex called the pars orbitalis, which is also involved in language comprehension. 0
Thagard; Brain and the Meaning of Life 163 Attending to music    also involves activation in an area of the right hemisphere    not used for language. 0
Thagard; Brain and the Meaning of Life 163 Perception of music    and memory for music    have common neural mechanisms    that explain how songs get stuck in our heads,    producing so-called earworms that are hard to stop. 0
Thagard; Brain and the Meaning of Life 163 Intense musical emotions --    thrills and chills --    are associated with brain regions involved in reward,    motivation,    and arousal:    the ventral striatum,    the amygdala,    the midbrain,    and regions of the frontal cortex. 0
Thagard; Brain and the Meaning of Life